Anti-RT1-D [OX-17]

Absolute Antibody

Anti-RT1-D [OX-17]

7

The OX-17 antigenic determinant is isotypic and on the alpha chain. OX-17 labels B but not T cells from lymph node or thoracic duct lymph but very weakly labels thymocytes and does not label erythrocytes. OX-17 does not cross-react with Rat Ia-A or Mouse

This antibody binds to rat MHC Class I, and has been used to show that, in an in vivo rat model, antibodies against MHC class I antigens from stored blood may precipitate transfusion-related acute lung injury (Kelher, 2009).

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, Other Application

WB; IP; IF; FC; depletion

Research Use Only

Monoclonal

OX-17

Rat

IgG2b

This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Rat

Rat

OX-17 was generated using BALB/c mice raised against rat spleen glycoproteins depleted of the Ia-A antigen using an OX-6 immunoaffinity column.

-20°C,2°C to 8°C

12352203