Anti-S100 alpha 6 Antibody [JF0976]

HUABIO

Anti-S100 alpha 6 Antibody [JF0976]

7

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,IP,FC

Research Use Only

Monoclonal

JF0976

1 mg/ml

Unconjugated

S100A6

S100 calcium binding protein A6

2A9, 5B10, CABP, CACY, PRA, S10A6, protein S100-A6, MLN 4, calcyclin, growth factor-inducible protein 2A9, prolactin receptor-associated protein

Rabbit

IgG

Protein S100-A6

Calcyclin, also known as Prolactin receptor-associated protein (PRA), growth factor-inducible protein 2A9, S-100 calcium-binding protein A6 (S-100A6) or MLN 4, is a homodimeric member of the S-100 calcium-binding protein family whose expression is upregulated in proliferating and differentiating cells. Calcyclin is inducible by growth factors and overexpressed in acute myeloid leukemias. It is expressed in a cell-specific manner in subpopulations of neurons and astrocytes and in epithelial cells and fibroblasts. Calcyclin is a specific target of S-100B protein in vivo. The binding of Calcyclin to S-100B is stabilized by S-100B-bound calcium and zinc. Calcyclin associates with both Annexin XI and CacyBP (calcyclin-binding protein). It functions to activate several processes along the calcium signal transduction pathway including the regulation of cell growth, proliferation, secretion and exocytosis.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161