Anti-SCLY Mouse mAb

PTM BIO

Anti-SCLY Mouse mAb

5

Western Blot

WB

Antibody

Research Use Only

Monoclonal

JMMR-1959

Unconjugated

Mouse

IgG

Selenocysteine lyase

Selenocysteine bèta-lyase (SCLY) works as a homodimer, utilizing pyridoxal 5’-phosphate as a cofactor, and catalyzing the specific decomposition of the amino acid selenocysteine into alanine and selenide. The enzyme is thought to deliver its selenide as a substrate for selenophosphate synthetases, which will ultimately be reutilized in selenoprotein synthesis. The highest SCLY expression and activity in mammals is found in the liver and kidneys. Disruption of the Scly gene in mice led to obesity, hyperinsulinemia, glucose intolerance, and hepatic steatosis.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse

Human, Mouse

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203