Anti-CXCL12/SDF1 Antibody [JJ09-20]

HUABIO

Anti-CXCL12/SDF1 Antibody [JJ09-20]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue

Research Use Only

Monoclonal

JJ09-20

1 mg/ml

Unconjugated

CXCL12

C-X-C motif chemokine ligand 12

IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, stromal cell-derived factor 1, chemokine (C-X-C motif) ligand 12, intercrine reduced in hepatomas, pre-B cell growth-stimulating factor

Rabbit

IgG

Stromal cell-derived factor 1

The stromal cell derived factor 1 (SDF1, CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1 isoforms (SDF1alpha and SDF1beta) that have different properties and biological activities. Additional isoforms of SDF1 have been reported.

Human

Human

-20°C,2°C to 8°C

41116161