Anti-Antithrombin III / ATIII / SERPINC1 Antibody [15F1]

HUABIO

Anti-Antithrombin III / ATIII / SERPINC1 Antibody [15F1]

7

Flow Cytometry, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,FC

Research Use Only

Monoclonal

15F1

2 mg/ml

Unconjugated

SERPINC1

serpin family C member 1

AT3, AT3D, ATIII, ATIII-R2, ATIII-T1, ATIII-T2, THPH7, antithrombin-III, serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1, serpin peptidase inhibitor clade C member 1, serpin peptidase inhibitor, clade C (antithrombin), member 1

Mouse

IgG1

Antithrombin-III

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.

Fish, Human, Mouse, Rat

Human,Mouse,Rat,Zebrafish

-20°C,2°C to 8°C

41116161