Anti-SETDB1 Mouse mAb

PTM BIO

Anti-SETDB1 Mouse mAb

5

Western Blot

WB

Antibody

Research Use Only

Monoclonal

10889

Unconjugated

Mouse

IgG

Histone-lysine N-methyltransferase SETDB1

Histone-lysine N-methyltransferase SETDB1 is an enzyme that in humans is encoded by the SETDB1 gene. SETDB1 is also known as KMT1E or H3K9 methyltransferase ESET. The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat, Monkey

Protein G purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203