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anti-SETMAR antibody

Research Use Only
ARG63243
Arigo Biolaboratories
ApplicationsWestern Blot
Product group Antibodies
ReactivityBovine, Human
TargetSETMAR
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-SETMAR antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6419
  • Target name
    SETMAR
  • Target description
    SET domain and mariner transposase fusion gene
  • Target synonyms
    histone-lysine N-methyltransferase SETMAR; Mar1; METNASE; SET domain and mariner transposase fusion gene-containing protein; SET domain and mariner transposase fusion protein
  • Host
    Goat
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
  • Reactivity
    Bovine, Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203