Anti-SHP2 Antibody [SN72-02]
ET1611-35
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetPTPN11
Overview
- SupplierHUABIO
- Product NameAnti-SHP2 Antibody [SN72-02]
- Delivery Days Customer7
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierWB,IP
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSN72-02
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5781
- Target namePTPN11
- Target descriptionprotein tyrosine phosphatase non-receptor type 11
- Target synonymsBPTP3, CFC, JMML, METCDS, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2, tyrosine-protein phosphatase non-receptor type 11, SH2 domain-containing protein tyrosine phosphatase 2, protein-tyrosine phosphatase 1D, protein-tyrosine phosphatase 2C
- HostRabbit
- IsotypeIgG
- Protein IDP35235
- Protein NameTyrosine-protein phosphatase non-receptor type 11
- Scientific DescriptionActs downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus .Positively regulates MAPK signal transduction pathway.Dephosphorylates GAB1, ARHGAP35 and EGFR.Dephosphorylates ROCK2 at Tyr-722 resulting in stimulation of its RhoA binding activity.Dephosphorylates CDC73.Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification.
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteMouse,Rat
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161