anti-SIRT4 antibody
ARG54660
ApplicationsWestern Blot, ELISA
Product group Antibodies
TargetSIRT4
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-SIRT4 antibody
- Delivery Days Customer23
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID23409
- Target nameSIRT4
- Target descriptionsirtuin 4
- Target synonymsNAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent protein deacetylase sirtuin-4; NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; regulatory protein SIR2 homolog 4; SIR2L4; sir2-like 4; SIR2-like protein 4; sirtuin type 4
- HostChicken
- IsotypeIgY
- Scientific DescriptionSIRT4 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion. -
- Storage Instruction-20°C
- UNSPSC12352203