Anti-SIRT5 Antibody [JJ084-01]

HUABIO

Anti-SIRT5 Antibody [JJ084-01]

7

Western Blot

WB

Research Use Only

Monoclonal

JJ084-01

1 mg/ml

Unconjugated

SIRT5

sirtuin 5

SIR2L5, NAD-dependent protein deacylase sirtuin-5, mitochondrial, NAD-dependent deacetylase sirtuin-5, NAD-dependent lysine demalonylase and desuccinylase sirtuin-5, mitochondrial, silent mating type information regulation 2, S.cerevisiae, homolog 5, sir2-like 5, sirtuin type 5

Rabbit

IgG

NAD-dependent protein deacylase sirtuin-5, mitochondrial

SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.

Human

Human

Mouse

-20°C,2°C to 8°C

41116161