anti-SLC7A11 / xCT antibody
![Research Use Only](static/images/certificates/ruo.jpg)
ARG57998
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman
TargetSLC7A11
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-SLC7A11 / xCT antibody
- Delivery Days Customer23
- ApplicationsImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23657
- Target nameSLC7A11
- Target descriptionsolute carrier family 7 member 11
- Target synonymsamino acid transport system xc-; calcium channel blocker resistance protein CCBR1; CCBR1; cystine/glutamate transporter; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; xCT
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203