Anti-Snake venom metalloproteinase BaP1 [MABaP1], Human IgG1, Fc Silent(tm), kappa

Absolute Antibody

Anti-Snake venom metalloproteinase BaP1 [MABaP1], Human IgG1, Fc Silent(tm), kappa

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This antibody reacts with snake venom metalloproteinase (SVMP) BaP1 present in the venom of Bothrops asper. BaP1 is a P-I class of SVMP relevant in the local tissue damage associated with envenomations by Bothrops asper. This metalloproteinase exhibits a

The antibody can bind snake venom metalloproteinases BaP1, whole venom of B. asper and BnP1 (B. neuwiedi) in an ELISA. This antibody completely neutralized in vivo hemorrhage, muscle necrosis, and inflammation induced by the toxin. This antibody completely neutralize myotoxicity induced by BaP1. In general it was capable of neutralizing biological effects of this SVMP (PMID: 20674587; 20674587).

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

MABaP1

Human

IgG1

This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Reptile

-20°C,2°C to 8°C

12352203