Anti-SNRPA1 Antibody [JE56-64]

HUABIO

Anti-SNRPA1 Antibody [JE56-64]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P

Research Use Only

Monoclonal

JE56-64

1 mg/ml

Unconjugated

SNRPA1

small nuclear ribonucleoprotein polypeptide A'

Lea1, U2A', U2 small nuclear ribonucleoprotein A', U2 small nuclear ribonucleoprotein polypeptide A', U2 snRNP A'

Rabbit

IgG

U2 small nuclear ribonucleoprotein A'

U2 SnRNP A Antibody (B-3) is a high quality monoclonal U2 SnRNP A antibody (also designated U2 SnRNP A antibody) suitable for the detection of the U2 SnRNP A protein of mouse, rat and human origin. U2 SnRNP A Antibody (B-3) is available as both the non-conjugated anti-U2 SnRNP A antibody form, as well as multiple conjugated forms of anti-U2 SnRNP A antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Small nuclear ribonucleoproteins, also known as snRNPs, combine with other proteins to form spliceosomes, a complex that catalyzes pre-mRNA splicing. There are two types of spliceosomes: U2 and U12. The U2-type spliceosome is found in all eukaryotes and excises U2-type introns, which account for the majority of pre-mRNA introns. The U12-type spliceosome removes U12-type introns, which comprise less than 1% of all human introns. U2 snRNP A, also known as SNRPA1 or U2A, is a component of the U2 snRNP that forms a complex with U2 snRNP B (U2B). Together, U2 snRNP A and U2 snRNP B form a complex that binds to the U2 snRNA hairpin IV. The configuration of this U2 snRNP A/U2 snRNP B dimer and the subtle variations of a few key residues regulate the snRNP-RNA-binding specificity. U2 snRNP A is a 255 amino acid protein, and two isoforms exist as a result of alternative splicing events.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161