Anti-SOD1 [B12], Human IgG1, lambda

Absolute Antibody

Anti-SOD1 [B12], Human IgG1, lambda

9

This antibody is specific for misfolded SOD1.

This antibody was used for a western blot on reacted against denatured wt and mt SOD1. It reacted to denatured wt, A4V and G93A SOD1 proteins but not the control SH3 protein. This antibody was used in vitro on NSC cells to determine the effect of the antibody on A4V and G93A mtSOD1 mediated cell death. The antibody has shown the ability to decrease the cell death caused by A4V and G93A mtSOD1 (Ghadge et al., 2014; PMID:23607939).

Western Blot, Other Application

Research Use Only

Monoclonal

B12

Human

IgG1

Human

-20°C,2°C to 8°C

12352203