Anti-SPATA5L1 Antibody

HUABIO

Anti-SPATA5L1 Antibody

7

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

AFG2B

AAA ATPase AFG2B

DFNB119, NEDHLS, SPATA5L1, ATPase family gene 2 protein homolog B, AFG2 AAA ATPase homolog B, ribosome biogenesis protein SPATA5L1, spermatogenesis associated 5 like 1, spermatogenesis-associated protein 5-like protein 1

Rabbit

IgG

ATPase family gene 2 protein homolog B

Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization.

Human

Human

-20°C,2°C to 8°C

41116161