Anti-Spike protein [18F4]

Absolute Antibody

Anti-Spike protein [18F4]

7

To characterize this antibody, an indirect ELISA was performed using the mouse version of this antibody. The antigen used was the SARS CoV2 spike protein. The mouse version of this antibody is capable of binding the S1 protein and blocking S1:ACE2 interaction. This antibody is reported to bind non-competitively with another anti-SARS CoV2 antibody D70678-5521-S2. Further, both biolayer interferometry and surface plasmon resonance were used to determine the kinetics of the mouse version of this antibody. Both experiments used the SARS CoV2 spike protein as the antigen (Mullen et al, 2021).

Functional Assay, ELISA, Neutralisation/Blocking, Other Application

Research Use Only

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203