Anti-SSRP1 Mouse mAb

PTM BIO

Anti-SSRP1 Mouse mAb

5

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin

WB, IHC-P, ICC/IF

Research Use Only

Monoclonal

JMMR-1962

Unconjugated

Mouse

IgG

FACT complex subunit SSRP1

FACT complex subunit SSRP1, also known as structure specific recognition protein 1, is a protein that in humans is encoded by the SSRP1 gene. SSRP1 is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. SSRP1 also functions as a co-activator of the transcriptional activator p63.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Human, Mouse, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203