Anti-STAT4 (Ab-693)

Applied Biological Materials

Anti-STAT4 (Ab-693)

9

STAT4 (Ab-693) antibody detects endogenous levels of total STAT4 protein.

Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 ug/ul

Rabbit

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]

Human, Mouse, Rat

-20°C,2°C to 8°C

12352203