Anti-STAT5b Mouse mAb

PTM BIO

Anti-STAT5b Mouse mAb

5

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

WB, ICC/IF

Antibody

Research Use Only

Monoclonal

JMMR-1276

Unconjugated

Mouse

IgG

Signal transducer and activator of transcription 5B

STAT5B belongs to the transcription factor STAT family. In response to cytokines and growth factors, STAT family members are Phosphorylatedrylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B carries out a dual function: signal transduction and activation of transcription. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different GH. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression.

Stable for 12 months from date of receipt/reconstitution.

Human, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203