Anti-Stella Antibody
R1306-1
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetDPPA3
Overview
- SupplierHUABIO
- Product NameAnti-Stella Antibody
- Delivery Days Customer7
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierWB,IHC-P
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID359787
- Target nameDPPA3
- Target descriptiondevelopmental pluripotency associated 3
- Target synonymsPgc7, STELLA, developmental pluripotency-associated protein 3, stella-related protein
- HostRabbit
- IsotypeIgG
- Protein IDQ6W0C5
- Protein NameDevelopmental pluripotency-associated protein 3
- Scientific DescriptionStella is a primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. It participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at Lys-9 (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. It is important for the totipotent/pluripotent states continuing through preimplantation development.
- ReactivityHuman, Mouse
- Reactivity SupplierHuman,Mouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161