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Anti-Succinyl-Histone H3 (Lys122) Rabbit pAb

PTM-413
PTM BIO
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
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Overview

  • Supplier
    PTM BIO
  • Product Name
    Anti-Succinyl-Histone H3 (Lys122) Rabbit pAb
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Applications Supplier
    WB
  • Category Supplier
    Antibody
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP68431
  • Protein Name
    Histone H3.1
  • Scientific Description
    Histones are subject to a variety of enzyme catalyzed modifications including acetylation, Phosphorylatedrylation, ubiquitylation etc. Lysine succinylation is a recently identified novel protein post-translational modification (PTM). Lysine succinylation is evolutionarily conserved and abundantly present in proteins in both prokaryotic and eukaryotic cells, suggesting its roles in regulating cellular physiology. This antibody will facilitate studies of lysine succinylation biology by identifying its substrates and studying its function.
  • Shelf life instruction
    Stable for 12 months from date of receipt/reconstitution.
  • Reactivity
    Human, Mouse, Rat
  • Reactivity Supplier
    Human, Mouse, Rat
  • Reactivity Supplier Note
    Protein A and immunogen affinity purified
  • Storage Instruction
    Store at -20°C. Avoid freeze/thaw cycles.
  • UNSPSC
    12352203

References

  • Bi Shijia, et al. 'SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer' Protein & Cell (2020)
    Read more
  • Yu Hai-Bo, et al. 'SIRT7 restricts HBV transcription and replication through catalyzing desuccinylation of histone H3 associated with cccDNA minichromosome' CLINICAL SCIENCE (2021)
    Read more
  • Qin Yi-Ping, et al. 'KAT2A Promotes Hepatitis B Virus Transcription and Replication Through Epigenetic Regulation of cccDNA Minichromosome' Frontiers in Microbiology (2022)
    Read more
  • Li Yinchuan, et al. 'Dynamic Profiles and Transcriptional Preferences of Histone Modifications During Spermiogenesis' ENDOCRINOLOGY (2020)
    Read more
  • Li Jialun, et al. 'HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation' Cell Discovery (2023)
    Read more
  • Keyu Chen, et al. 'SIRT7 knockdown promotes gemcitabine sensitivity of pancreatic cancer cell via upregulation of GLUT3 expression' CANCER LETTERS (2024)
    Read more