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Anti-Succinyl-Histone H3 (Lys14) Mouse mAb

PTM-421
PTM BIO
ApplicationsWestern Blot, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
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Overview

  • Supplier
    PTM BIO
  • Product Name
    Anti-Succinyl-Histone H3 (Lys14) Mouse mAb
  • Delivery Days Customer
    5
  • Antibody Specificity
    Anti-Succinyl-Histone H3 (Lys14) Mouse mAb detects histone H3 only when it is succinylated at Lys14.
  • Applications
    Western Blot, ImmunoHistoChemistry Paraffin
  • Applications Supplier
    WB, IHC-P
  • Category Supplier
    Antibody
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Conjugate
    Unconjugated
  • Host
    Mouse
  • Isotype
    IgG
  • Protein IDP68431
  • Protein Name
    Histone H3.1
  • Scientific Description
    Histones are subject to a variety of enzyme catalyzed modifications including acetylation, Phosphorylatedrylation, ubiquitylation etc. Lysine succinylation is a recently identified novel protein post-translational modification (PTM). Lysine succinylation is evolutionarily conserved and abundantly present in proteins in both prokaryotic and eukaryotic cells, suggesting its roles in regulating cellular physiology. This antibody is specifically designed to facilitate studies of lysine succinylation by enabling the identification of succinylation substrates and providing insights into its functional roles.
  • Shelf life instruction
    Stable for 12 months from date of receipt/reconstitution.
  • Reactivity
    Human, Mouse, Rat
  • Reactivity Supplier
    Human, Mouse, Rat
  • Reactivity Supplier Note
    Protein G and immunogen affinity purified
  • Storage Instruction
    Store at -20°C. Avoid freeze/thaw cycles.
  • UNSPSC
    12352203

References

  • Li Jialun, et al. 'HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation' Cell Discovery (2023)
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