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anti-TCEB1 antibody

ARG58449
Arigo Biolaboratories
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetELOC

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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-TCEB1 antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID6921
  • Target name
    ELOC
  • Target description
    elongin C
  • Target synonyms
    SIII, TCEB1, elongin-C, RNA polymerase II transcription factor SIII subunit C, SIII p15, elongin 15 kDa subunit, transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C), transcription elongation factor B polypeptide 1, transcription elongation factor B subunit 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203