Anti-TCEB2 Antibody [JE65-72]

HUABIO

Anti-TCEB2 Antibody [JE65-72]

2

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

JE65-72

1 mg/ml

Unconjugated

ELOB

elongin B

SIII, TCEB2, elongin-B, RNA polymerase II transcription factor SIII p18 subunit, RNA polymerase II transcription factor SIII subunit B, SIII p18, elongin 18 kDa subunit, elongin, 18-kD subunit, epididymis secretory sperm binding protein, transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B), transcription elongation factor B polypeptide 2, transcription elongation factor B subunit 2

Rabbit

IgG

Elongin-B

Elongin B is a protein that in humans is encoded by the ELOB gene.Elongin B is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

-20°C,2°C to 8°C

41116161