Anti-TCF3 Antibody [SY0258]

HUABIO

Anti-TCF3 Antibody [SY0258]

7

Flow Cytometry, Western Blot

WB,FC

Research Use Only

Monoclonal

SY0258

1 mg/ml

Unconjugated

TCF7L1

transcription factor 7 like 1

transcription factor 7-like 1, HMG box transcription factor 3, transcription factor 7-like 1 (T-cell specific, HMG-box)

Rabbit

IgG

Transcription factor 7-like 1

Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development include Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and heterooligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.

Human

Human

-20°C,2°C to 8°C

41116161