Anti-Testosterone [3C4F5]

Absolute Antibody

Anti-Testosterone [3C4F5]

7

The original mouse IgG2b version of this antibody binds testosterone with an affinity of 0.3 nM. The binding properties of the antibody was preliminarily characterized by a competitive enzyme-linked immunosorbent assay. The combined (44 + 28) mutant derived from this antibody showed less cross-reactivity towards DHEAS of 0.033%, 44-fold less than in the wild-type (Hemminki et al, 1998; pmid:9680193). The combined mutant is available on request. To elucidate the structure of the mouse version of this antibody bound to testosterone x-ray crystallography was performed (Valjakka et al, 2002; pmid:11707437).

Functional Assay, ELISA

ELISA; functional assay

Research Use Only

Monoclonal

3C4F5

Human

IgG1

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

41116161