Anti-Testosterone [5F2]

Absolute Antibody

Anti-Testosterone [5F2]

9

The testosterone binding affinity of the 5F2 Fab fragment is 900 nM as determined by a competitive ELISA. Binding specificity of the 5F2 Fab was also studied by using 5alpha- dihydrotestosterone, dehydroepiandrosterone sulphate and androstenedione. Furthermore the Fab version of this antibody was co-crystallized with testosterone and the structure was identified using x-ray crystallography (Niemi et al, 2011; pmid:21360611).

Functional Assay, ELISA

Research Use Only

Monoclonal

5F2

Human

IgG1

This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.

Other Species

-20°C,2°C to 8°C

41116161