Anti-Tet1 Antibody

HUABIO

Anti-Tet1 Antibody

7

Flow Cytometry, ImmunoFluorescence, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

IHC-P,FC,IF-Cell

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Tet1

tet methylcytosine dioxygenase 1

2510010B09Rik, Cxxc6, D10Ertd17e, LCX, mKIAA1676, methylcytosine dioxygenase TET1, CXXC finger 6, CXXC-type zinc finger protein 6, ten-eleven translocation 1 gene protein homolog, tet oncogene 1

Rabbit

IgG

Methylcytosine dioxygenase TET1

TET1 (tet oncogene 1), also known as LCX or CXXC6, is a 2,136 amino acid protein that localizes to the nucleus and contains one CXXC-type zinc finger. Expressed in adult ovary, thymus and skeletal muscle and also present in fetal lung, heart and brain, TET1 is thought to play a role in the development of fetal organs and may also be involvement in the pathoegenesis and metastasis of acute myeloid leukemia (AML). The gene encoding TET1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolmans syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161