Anti-Thymidine Kinase 1 Antibody [JF0970]

HUABIO

Anti-Thymidine Kinase 1 Antibody [JF0970]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,IP,FC

Research Use Only

Monoclonal

JF0970

1 mg/ml

Unconjugated

TK1

thymidine kinase 1

TK2, thymidine kinase, cytosolic, cytosolic thymidine kinase, epididymis secretory sperm binding protein

Rabbit

IgG

Thymidine kinase, cytosolic

Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division. Because of this, Thymidine Kinase can be used as a proliferation marker in the diagnosis, treatment, and follow-up of malignant diseases, especially hematological malignancies. Thymidine Kinase may be observed as a monomer, dimer, trimer or tetramer.

Human, Mouse

Human,Mouse

-20°C,2°C to 8°C

41116161