anti-TIRAP antibody
ARG55409
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityMouse, Rat
TargetTirap
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-TIRAP antibody
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID117149
- Target nameTirap
- Target descriptiontoll-interleukin 1 receptor (TIR) domain-containing adaptor protein
- Target synonymsAA407980; adaptor protein Wyatt; C130027E04Rik; M; Mal; myD88 adapter-like protein; TIR domain-containing adapter protein; Tlr4ap; toll/interleukin-1 receptor domain-containing adapter protein; Toll-like receptor 4 adaptor protein; wyat; Wyatt
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
- ReactivityMouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203