ProductsBack/Anti-Topoisomerase I Rabbit mAb

Anti-Topoisomerase I Rabbit mAb

Name: Anti-Topoisomerase I Rabbit mAb
SKU: PTM-6388_P78
Availability: BackOrder

PTM-6388

ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rat

Overview

Supplier
PTM BIO
Product Name
Anti-Topoisomerase I Rabbit mAb
Delivery Days Customer
5
Applications
Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin
Applications Supplier
WB, IHC-P, ICC/IF, FC, IP
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
JRMR-10808-46
Conjugate
Unconjugated
Host
Rabbit
Isotype
IgG
Protein IDP11387
Protein Name
DNA topoisomerase 1
Scientific Description
DNA topoisomerases play essential roles in many DNA metabolic processes including DNA repair. Topoisomerases can introduce DNA damage upon exposure to drugs that stabilize the covalent protein-DNA intermediate of the topoisomerase reaction. Lesions in DNA are also able to trap topoisomerase-DNA intermediates. DNA topoisomerase I (Top1) catalyzes the relaxation of supercoiled DNA by a mechanism of transient DNA strand cleavage characterized by the formation of a Phosphorylatedtyrosyl bond between the DNA end and active site tyrosine.
Shelf life instruction
Stable for 12 months from date of receipt/reconstitution.
Reactivity
Human, Mouse, Rat
Reactivity Supplier
Human, Mouse, Rat
Reactivity Supplier Note
Protein A purified
Storage Instruction
Store at -20°C. Avoid freeze/thaw cycles.
UNSPSC
12352203