Anti-toxin A [A26.8], Rabbit IgG-Fc Fusion,

Absolute Antibody

Anti-toxin A [A26.8], Rabbit IgG-Fc Fusion,

9

The antibody is specific for toxin A of Clostridium difficile. It recognises a conformational epitope on native C. difficile toxin.

The specificity of the original format of the antibody to TcdA was confirmed by ELISA analysis. The binding affinity of the original format of the antibody was measured by surface plasmon resonance (Kd= 12 nM). Human lung fibroblast (HLF) cytotoxicity assay was used to determine whether the original format of the antibody could neutralize TcdA-induced HLF cell rounding. The antibody showed neutralizing activity to TcdA (US9771416B2).

ELISA, Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

A26.8

Rabbit

IgG

Toxin A

This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.

Bacteria

-20°C,2°C to 8°C

12352203