anti-TRAIL-R1 (human), mAb (TR1.02)

AdipoGen Life Sciences

anti-TRAIL-R1 (human), mAb (TR1.02)

10

Flow Cytometry, ImmunoHistoChemistry

Research Use Only

Monoclonal

TR1.02

1 mg/ml

>95%

TNFRSF10A

TNF receptor superfamily member 10a

APO2, CD261, DR4, TRAILR-1, TRAILR1, tumor necrosis factor receptor superfamily member 10A, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, cytotoxic TRAIL receptor, death receptor 4, tumor necrosis factor receptor superfamily, member 10a

Mouse

IgG2b

Tumor necrosis factor receptor superfamily member 10A

Monoclonal Antibody. Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3 or -R4. Isotype: Mouse IgG2b. Clone: TR1.02. Applications: FACS, IHC. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. - TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

Human

-20°C,2°C to 8°C

12352203