anti-TRAIL-R2 (human), mAb (HS201)

AdipoGen Life Sciences

anti-TRAIL-R2 (human), mAb (HS201)

10

Flow Cytometry, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, Neutralisation/Blocking

Research Use Only

Monoclonal

HS201

1 mg/ml

>95%

TNFRSF10B

TNF receptor superfamily member 10b

apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; CD262; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; DR5; Fas-like protein; KILLER; KILLER/DR5; p53-regulated DNA damage-inducible cell death receptor(killer); TNF-related apoptosis-inducing ligand receptor 2; TRAILR2; TRAIL-R2; TRICK2; TRICK2A; TRICK2B; TRICKB; tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9; ZTNFR9

Mouse

IgG1

Tumor necrosis factor receptor superfamily member 10B

Monoclonal Antibody. Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4. Isotype: Mouse IgG1. Clone: HS201. Applications: FACS, FUNC (Blocking), ICC, IHC, IP. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. - TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. Negative regulator of p53.

-20°C,2°C to 8°C

12352203