Anti-TRIM24 Antibody [JE64-31]

HUABIO

Anti-TRIM24 Antibody [JE64-31]

2

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

JE64-31

1 mg/ml

Unconjugated

TRIM24

tripartite motif containing 24

PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1, transcription intermediary factor 1-alpha, E3 ubiquitin-protein ligase TRIM24, RING finger protein 82, RING-type E3 ubiquitin transferase TIF1-alpha, TIF1-alpha, transcriptional intermediary factor 1

Rabbit

IgG

Transcription intermediary factor 1-alpha

Tripartite motif-containing 24 (TRIM24) also known as transcriptional intermediary factor 1alpha (TIF1alpha) is a protein that, in humans, is encoded by the TRIM24 gene. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. TRIM24 has been shown to interact with Mineralocorticoid receptor, TRIM33, Estrogen receptor alpha and Retinoid X receptor alpha.

-20°C,2°C to 8°C

41116161