Anti-TRIP8b (exon 1a/5) [N291C/22]

Absolute Antibody

Anti-TRIP8b (exon 1a/5) [N291C/22]

7

This antibody is specific for exon 1a/5 junction of TRIP8b. TRIP8b is an accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence.

This antibody is recommended for the detection and analysis of TRIP8b by immunocytochemsitry and western blot. For instance, the mouse version of this antibody was used to detect TRIP8b by western blot in extracts of COS cells transiently transfected with carboxyterminally (C) and amino-terminally (N) GFPtagged TRIP8b-1a-5, TRIP8b-1a-4 or untagged Kv2.1 plasmid. Furthermore TRIP8b was also detected by western blot in crude membranes from adult rat brain and WT and TRIP8b KO mouse brains probed with N291C/22 and N52A/42 TC supe.

Western Blot, ImmunoCytoChemistry

ICC; WB

Research Use Only

Monoclonal

N291C/22

Pex5l

peroxisomal biogenesis factor 5-like

peroxin 2; peroxin-5-related protein; Pex2; PEX5-like protein; PEX5-related protein; pex5Rp; tetratricopeptide repeat-containing Rab8b-interacting protein; TPR-containing Rab8b-interacting protein; TRIP8b; Trjip8b

Rat

IgG2b

PEX5-related protein

This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Mouse, Rat

mouse, rat

This antibody was raised by immunising BALB/c mice with a synthetic peptide amino acids 1-12 (MYQGHMQLVNEQ, exon 1a (yellow) and exon 5 (green) of constant region) of mouse TRIP8b.

-20°C,2°C to 8°C

12352203