Anti-TRP-1, gp75 [TA99]

Absolute Antibody

Anti-TRP-1, gp75 [TA99]

7

Binds Tyrosinase-related protein-1 (TRP-1), a 70-75k enzyme located in melanocytes, which are specialized cells that produce a pigment called melanin, helping to stabilize tyrosinase, which is the enzyme responsible for the first step in melanin productio

This antibody binds to human and murine TRP-1 and had been under evaluation for the treatment of tumours.

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

ELISA; FC; IF; IHC-Fr; IP; WB

Research Use Only

Monoclonal

TA99

TYRP1

tyrosinase related protein 1

5,6-dihydroxyindole-2-carboxylic acid oxidase; b-PROTEIN; CAS2; catalase B; CATB; DHICA oxidase; glycoprotein 75; GP75; melanoma antigen gp75; OCA3; TRP; TRP1; TYRP

Mouse

IgG2a

5,6-dihydroxyindole-2-carboxylic acid oxidase

This is a bispecific, knob-into-hole heterodimerized antibody, with one arm directed against TRP-1 (Fab) and one arm directed against mouse CD3e (scFv).

Human

Human

70-75 kDa pigmentation-associated glycoprotein in human melanoma cell lines.

-20°C,2°C to 8°C

12352203