Anti-UBA3 Antibody [1C10-5-5]

HUABIO

Anti-UBA3 Antibody [1C10-5-5]

7

Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,FC

Research Use Only

Monoclonal

1C10-5-5

2 mg/ml

Unconjugated

UBA3

ubiquitin like modifier activating enzyme 3

NAE2, UBE1C, hUBA3, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 subunit 2, NEDD8-activating enzyme E1C, Nedd8-activating enzyme hUba3, UBA3, ubiquitin-activating enzyme E1 homolog, ubiquitin-activating enzyme 3, ubiquitin-activating enzyme E1C (UBA3 homolog, yeast), ubiquitin-activating enzyme E1C (homologous to yeast UBA3)

Mouse

IgG1

NEDD8-activating enzyme E1 catalytic subunit

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Human

Human

-20°C,2°C to 8°C

41116161