Anti-UQCRH Antibody [JE62-25]

HUABIO

Anti-UQCRH Antibody [JE62-25]

2

Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

JE62-25

1 mg/ml

Unconjugated

UQCRH

ubiquinol-cytochrome c reductase hinge protein

MC3DN11, QCR6, UQCR8, cytochrome b-c1 complex subunit 6, mitochondrial, complex III subunit 6, cytochrome c1 non-heme 11 kDa protein, mitochondrial hinge protein, ubiquinol-cytochrome c reductase complex 11 kDa protein, ubiquinol-cytochrome c reductase, complex III subunit VIII

Rabbit

IgG

Cytochrome b-c1 complex subunit 6, mitochondrial

Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.

-20°C,2°C to 8°C

41116161