Anti-UTF1 Antibody [E0-F4]
M1407-6
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetUTF1
Overview
- SupplierHUABIO
- Product NameAnti-UTF1 Antibody [E0-F4]
- Delivery Days Customer7
- ApplicationsImmunoFluorescence, Western Blot
- Applications SupplierWB,IF-Cell
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDE0-F4
- Concentration2 mg/ml
- ConjugateUnconjugated
- Gene ID8433
- Target nameUTF1
- Target descriptionundifferentiated embryonic cell transcription factor 1
- Target synonymsundifferentiated embryonic cell transcription factor 1
- HostMouse
- IsotypeIgG2b
- Protein IDQ5T230
- Protein NameUndifferentiated embryonic cell transcription factor 1
- Scientific DescriptionUndifferentiated embryonic cell transcription factor 1 is a protein in humans that is encoded by the UTF1 gene. UTF1, first reported in 1998, is expressed in pluripotent cells including embryonic stem cells and embryonic carcinoma cells. Its expression is rapidly reduced upon differentiation. UTF1 protein is localized to the cell nucleus, where it functions to regulate the pluripotent chromatin state and buffer mRNA levels by promoting degradation of mRNA. Aberrant expression of UTF1 has also been reported in cervical cancer cells, where the UTF1 gene promoter loses methylation and becomes abnormally expressed compared to normal cervical cells.
- ReactivityHuman, Mouse, Rat
- Reactivity SupplierHuman,Mouse,Rat
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161