Anti-UTF1 Antibody
R1305-4
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetUTF1
Overview
- SupplierHUABIO
- Product NameAnti-UTF1 Antibody
- Delivery Days Customer7
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierWB,IHC-P
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8433
- Target nameUTF1
- Target descriptionundifferentiated embryonic cell transcription factor 1
- Target synonymsundifferentiated embryonic cell transcription factor 1
- HostRabbit
- IsotypeIgG
- Protein IDQ5T230
- Protein NameUndifferentiated embryonic cell transcription factor 1
- Scientific DescriptionUndifferentiated embryonic cell transcription factor 1 (UTF1) is expressed in cells of the inner cell mass and the epiblast. Upon activation by Oct-3/4, UTF1 may be responsible for the rapid proliferation and tumorigenic properties of embryonic stem cells. Sox2 is also part of the Oct-3/4-containing complex able to bind the regulatory region of UTF1. UTF1 acts as a transcriptional coactivator of ATF2 and it binds to the N-terminal region of ATF2. Reduced expression in embryonic stem cells (ESCs) is associated with failure to differentiate properly, although self-renewal is unaffected.
- ReactivityHuman, Mouse, Rat
- Reactivity SupplierHuman,Mouse,Rat
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161