Anti-VISTA Neutralizing Antibody

BPS Bioscience

Anti-VISTA Neutralizing Antibody

7

The antibody recognizes a unique epitope on the surface of human VISTA protein. It has not been tested on other species

Neutralisation/Blocking

Research Use Only

Monoclonal

VSIR

V-set immunoregulatory receptor

B7H5; B7-H5; C10orf54; DD1alpha; Death Domain1alpha; Dies1; GI24; PD-1H; PDCD1 homolog; platelet receptor GI24; PP2135; SISP1; sisp-1; stress-induced secreted protein-1; V-domain Ig suppressor of T cell activation; VISTA; V-set domain-containing immunoregulatory receptor; V-type immunoglobulin domain-containing suppressor of T-cell activation

Human

IgG1

This human monoclonal antibody recognizes human V-domain immunoglobulin (Ig) suppressor of T cell activation (VISTA), and neutralizes its interaction with VSIG3 (also called IGSF11). VISTA is also known as B7-H5 or VSIR (GenBank Accession No. NM_022153). VSIG3 is a ligand involved in cell adhesion as a VISTA binding partner. This neutralizing antibody has been functionally tested using the VSIG-3:VISTA [Biotinylated] Inhibitor Screening Assay Kit (BPS Bioscience #79782).

-80°C

12352203