Anti-VISTA Neutralizing Antibody

BPS Bioscience

Anti-VISTA Neutralizing Antibody

7

Neutralisation/Blocking

Research Use Only

Monoclonal

VSIR

V-set immunoregulatory receptor

B7-H5, B7H5, C10orf54, DD1alpha, Dies1, GI24, PD-1H, PP2135, SISP1, VISTA, V-type immunoglobulin domain-containing suppressor of T-cell activation, Death Domain1alpha, PDCD1 homolog, V-domain Ig suppressor of T cell activation, V-set domain-containing immunoregulatory receptor, platelet receptor GI24, sisp-1, stress-induced secreted protein-1

Human

IgG1

V-type immunoglobulin domain-containing suppressor of T-cell activation

This human monoclonal antibody recognizes human V-domain immunoglobulin (Ig) suppressor of T cell activation (VISTA), and neutralizes its interaction with VSIG3 (also called IGSF11). VISTA is also known as B7-H5 or VSIR (GenBank Accession No. NM_022153). VSIG3 is a ligand involved in cell adhesion as a VISTA binding partner. This neutralizing antibody has been functionally tested using the VSIG-3:VISTA [Biotinylated] Inhibitor Screening Assay Kit (BPS Bioscience #79782).

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