Anti-WDR77 Antibody [PSH0-07]

HUABIO

Anti-WDR77 Antibody [PSH0-07]

2

Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

PSH0-07

1 mg/ml

Unconjugated

WDR77

WD repeat domain 77

HKMT1069, MEP-50, MEP50, Nbla10071, p44, p44/Mep50, methylosome protein WDR77, WD repeat-containing protein 77, androgen receptor cofactor p44, methylosome protein 50, testis tissue sperm-binding protein Li 44a

Rabbit

IgG

Methylosome protein WDR77

Methylosome protein 50 is a protein that in humans is encoded by the WDR77 gene. Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The methylosome complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

-20°C,2°C to 8°C

41116161