Anti-XBP1 Antibody [JM10-62]
ET1703-23
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetXBP1
Overview
- SupplierHUABIO
- Product NameAnti-XBP1 Antibody [JM10-62]
- Delivery Days Customer7
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierWB,IHC-P,IF-Cell,IF-Tissue,FC
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJM10-62
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7494
- Target nameXBP1
- Target descriptionX-box binding protein 1
- Target synonymsTREB-5, TREB5, XBP-1, XBP2, X-box-binding protein 1, tax-responsive element-binding protein 5
- HostRabbit
- IsotypeIgG
- Protein IDO35426
- Protein NameX-box-binding protein 1
- Scientific DescriptionX-box binding protein 1, also known as XBP1, is a protein which in humans is encoded by the XBP1 gene. The XBP1 protein is a transcription factor that regulates the expression of genes important to the proper functioning of the immune system and in the cellular stress response. It was first identified by its ability to bind to the Xbox, a conserved transcriptional element in the promoter of the human leukocyte antigen (HLA) DR alpha. Abnormalities in XBP1 lead to a heightened ER stress and subsequently causes a heightened susceptibility for inflammatory processes that may contribute to Alzheimers disease. In the colon, XBP1 anomalies have been linked to Crohns disease.
- ReactivityHuman
- Reactivity SupplierHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161