Anti-YARS2 Antibody

HUABIO

Anti-YARS2 Antibody

7

ImmunoFluorescence, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

IF-Tissue,IHC-P

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Rabbit

IgG

Tyrosine--tRNA ligase

Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). Defects in YARS2 are the cause of myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2) [MIM:613561]. MLASA2 is a rare oxidative phosphorylation disorder specific to skeletal muscle and bone marrow. Affected individuals manifest sideroblastic anemia, progressive lethargy, muscle weakness, and exercise intolerance associated with persistent lactic acidemia.

Fish

Zebrafish

-20°C,2°C to 8°C

41116161