Anti-YY1 Antibody [SY29-01]

HUABIO

Anti-YY1 Antibody [SY29-01]

7

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,IP

Research Use Only

Monoclonal

SY29-01

1 mg/ml

Unconjugated

YY1

YY1 transcription factor

DELTA, GADEVS, INO80S, NF-E1, UCRBP, YIN-YANG-1, transcriptional repressor protein YY1, INO80 complex subunit S, YY-1, Yin and Yang 1 protein, delta transcription factor

Rabbit

IgG

Transcriptional repressor protein YY1

The YY1 transcription factor, also known as NF-E1 (human) and Delta or UCRBP (mouse) is of interest due to its diverse effects on a wide variety of target genes. YY1 is broadly expressed in a wide range of cell types and contains four C-terminal zinc finger motifs of the Cys-Cys-His-His type and an unusual set of structural motifs at its N-terminal. It binds to downstream elements in several vertebrate ribosomal protein genes, where it apparently acts positively to stimulate transcription and can act either negatively or positively in the context of the immunoglobulin k 3 enhancer and immunoglobulin heavy-chain microE1 site as well as the P5 promoter of the adeno-associated virus. It thus appears that YY1 is a bifunctional protein, capable of functioning as an activator in some transcriptional control elements and a repressor in others.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161