Antibacterial agent 102

MedChem Express

Antibacterial agent 102 [2413293-65-7]

10

Research Use Only

C35H49N5O5S

651.86

Antibacterial agent 102 (compound 32) possesses potent in vitro and in vivo antibacterial activity, with MICs Staphylococcus aureus (S. aureus). Antibacterial agent 102 also moderately inhibits CYP3A4 with an IC50 value of 6.148 microM. Antibacterial agent 102 can reduce Methicillin-resistant Staphylococcus aureus (MRSA) load in thigh infected mice[1].

O=C(O[C@H]1[C@]2(C)[C@@H](CC[C@]3([C@H]([C@@H]([C@](C=C)(C1)C)O)C)[C@]2(C(CC3)=O)[H])C)CSC4=C(NC(CN5C=C(CN(C)C)N=N5)=O)C=CC=C4

12131703