Anticancer agent 109 [2097497-16-8]

TargetMol Chemicals

Anticancer agent 109 [2097497-16-8]

16

Research Use Only

C19H15N3O2

317.34

Anticancer agent 109 (compound 6-15) acts as an inhibitor targeting the Gas6-Axl axis, demonstrating significant anti-cancer properties. This compound suppresses the expression of Gas6, Axl, p-PI3K, and p-AKT in cancer cells, thereby inducing G1 phase arrest and promoting apoptosis of cancer cells. Additionally, Anticancer agent 109 effectively inhibits tumor growth in nude mouse tumor-bearing models [1].

C(=C\1/C=2C(NC1=O)=NC(C)=C(O)C2C)\C3=NC4=C(C=C3)C=CC=C4

-20°C

12352200