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Anticancer agent 139

HY-149388
MedChem Express
Molecular Weight319.28
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Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Anticancer agent 139 [2954795-29-8]
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C16H12F3N3O
  • Molecular Weight
    319.28
  • Scientific Description
    Anticancer agent 139 (Compound 6h) has potent anticancer activity. Anticancer agent 139 displayed a pi-cationic interaction with the residue Lys352 of Tublin. Anticancer agent 139 has good anticancer activity against SNB-19, OVCAR-8, and NCI-H40 with PGIs of 86.61, 85.26, and 75.99, respectively. Anticancer agent 139 also has moderate anticancer activity against HOP-62, SNB-75, ACHN, NCI/ADR-RES, 786-O, A549/ATCC, HCT-116, and MDA-MB-231 with PGIs of 67.55, 65.46, 59.09, 59.02, 57.88, 56.88, 56.53, 56.4, and 51.88 respectively[1].
  • SMILES
    CC1=CC(C)=C(C=C1)NC2=NN=C(O2)C3=CC(F)=C(C(F)=C3)F
  • UNSPSC
    12131703