Anticancer agent 157
HY-149523
Molecular Weight220.31
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameAnticancer agent 157
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC14H20O2
- Molecular Weight220.31
- Scientific DescriptionAnticancer agent 157 (compound 15) is a NO inhibitor (IC50=0.62 microg/mL) with anti-inflammatory and anticancer activities. Anticancer agent 157 can bind to iNOS (inducible NO synthase) and caspase 8, causing nuclear fragmentation and chromatin condensation, inducing apoptosis. Anticancer agent 157 inhibits HT29 colon cancer cells (IC50=2.45 microg/mL), Hep-G2 liver cancer cells (IC50=3.25 microg/mL), and B16-F10 murine melanoma cells (IC50=3.84 microg/mL)[1].
- SMILESOC1=C(CO)C(C)=C2CCCC(C)(C)C2=C1
- UNSPSC12131703